On the anniversary of the COVID-19 shutdown, President Biden in his speech noted COVID-19 has had a significant impact on everyone’s lives and that “while it was different for everyone, we all lost something.” We must acknowledge that Black, Indigenous and People of Color (BIPOC) have larger losses, in comparison to Whites. The losses that BIPOC, and especially Latinos, have experienced during COVID-19 have important implications for stress, and consequently mental health outcomes. We must recognize the major stressors Latino families are facing under COVID-19 so that we can address the health needs of this group as we move forward.